The FOx BIOSYSTEMS instrument is effective in studying affinity and binding kinetics of proteins on large particles, such as cells, viruses and microvesicles. The dip-in probe format even allows for biopanning, an affinity selection technique that is used to isolate phage displaying a peptide that binds to a given target.
Furthermore, the fluidics-free setup provides an advantage over existing biosensor platforms by eliminating the risk of clogging associated with cells and filamentous bacteria. In microfluidic instruments, this clogging necessitates time-consuming rinsing procedures and may impact accuracy.